Brain metastases (bm) are an important cause of morbidity and mortality and represent the most common intracranial tumors in adults, occurring in 2030 of cancer patients (langer and mehta, 2005 khuntia et al.).
В brain metastases are most common in the advanced stages of disseminated disease, but can occur in isolation. Tumour seeding of the brain parenchyma involves a number of steps, including intravasation (reaching the brain vasculature), breaching of the blood-brain barrier, and proliferation and neoangiogenesis (the formation of new blood vessels.).
В brain metastases are the most common intracranial neoplasm in adults. They often originate from lung cancer, breast cancer or melanoma, but also other malignancies like renal cancer, colorectal cancer and ovarian cancer are increasingly associated with brain metastases.
Even malignant pituitary tumors rarely spread to other parts of the body. Adenomas are by far the most common disease affecting the pituitary. They commonly affect people in their 30s or 40s, although they are diagnosed in children, as well.
В brain metastases are cancer cells that have spread to the brain from primary tumors in other organs in the body (see the image below). Metastatic tumors are among the most common mass lesions in the brain. An estimated 24-45 of all cancer patients in the united states have brain metastases.
Metastatic brain tumors are the most common brain tumor in adults. The exact incidence of metastatic brain tumors is not known but is estimated between 200,000 and 300,000 people per year.
Lung cancer, breast cancer, and melanoma are the most common primary tumors that lead to the formation of brain metastases in adults and account for 6780 of all cancers. In about 10 of patients with brain metastases, the primary tumor is unknown (cancer of unknown primary, cup) (1, 4).
Systemic cancer is the second most common cause of death for adults in the united states. Brain metastases occur most frequently in lung cancer (48) and.